Polynucleotides
Next-generation bio-stimulation for skin that regenerates itself. The treatment that works while you wait
£35 consultation fee is redeemable against your first treatment.
What It Is
Polynucleotides are bio-stimulating compounds derived from purified DNA fragments that trigger your body's own cellular regeneration. Unlike fillers or toxins, they work at the deepest level, stimulating fibroblasts to produce new collagen, elastin, and healthy tissue from within.
This is one of the most advanced regenerative treatments we offer at Éclat & Harmonie, and it requires careful assessment. During your consultation, Zaara will evaluate whether polynucleotides are the right approach for your concern, particularly for delicate areas like the under-eyes and neck where other treatments may not be suitable.
Results develop progressively over 4–8 weeks as tissue genuinely regenerates, with improvements continuing for months. Effects last 12 months or longer. This treatment is also highly effective for hair thinning, stimulating dormant follicles to produce new growth.
Why Choose Polynucleotides?
Works at a cellular level, regenerating tissue rather than masking the signs of ageing
Particularly effective for delicate under-eye skin where other treatments can't safely go
Long-lasting results (12+ months) that continue to improve after your final session
A thorough consultation ensures this advanced treatment is correctly matched to your needs
Duration
30–45 min
Downtime
Minimal
Results
2–6 weeks
How It Works
Tissue Assessment
Your practitioner examines the target area for signs of skin laxity, dehydration, or damage to determine the optimal injection technique and depth. This assessment ensures the treatment addresses your specific tissue concerns.
Precision Injection
Polynucleotide gel derived from purified DNA fragments is injected using a fine needle or cannula into areas requiring deep tissue regeneration. Placement is specific to the anatomy of each treatment zone.
Bio-Stimulation Activation
The polynucleotides integrate with your tissue, stimulating fibroblast activity, promoting new collagen and elastin production, and improving blood flow to the treated area.
Tissue Remodelling
Visible improvement in skin quality, firmness, and hydration develops over 3–6 weeks. A course of 2–3 sessions spaced 3–4 weeks apart delivers significant, long-lasting results.
Treatment at a Glance
Best For
Clients seeking deep skin regeneration and bio-stimulation rather than volume or wrinkle-freezing. Ideal for under-eye rejuvenation, skin laxity, dull or tired-looking skin, and hair thinning. Particularly effective for delicate areas like under-eyes and neck where other treatments may not be suitable. Ages 30+.
Not Suitable If
Pregnant or breastfeeding, known allergy to salmon-derived products (polynucleotides are typically derived from salmon DNA), active infection or inflammation at treatment site, autoimmune conditions, currently on anticoagulant medication without medical clearance.
Results Timeline
Initial improvement in skin hydration and texture visible within 1–2 weeks. Bio-stimulation effects (collagen and elastin regeneration) develop progressively over 4–8 weeks. Full rejuvenation results typically visible after completing a course of sessions, with benefits lasting 6–12 months.
Downtime
Minimal. Small injection marks, mild swelling, and potential bruising, particularly in the under-eye area where skin is thinner. Swelling typically subsides within 2–3 days. Most clients return to normal activities immediately. Avoid makeup for 12 hours and intense exercise for 24 hours.
Sessions Recommended
A course of 2–3 sessions spaced 3–4 weeks apart is recommended for optimal bio-stimulation. Under-eye treatments may require 2–4 sessions depending on severity. Maintenance sessions every 6–12 months to sustain regeneration benefits.
Consultation Required
A specialist consultation is required to assess your skin's regenerative needs and determine the most effective treatment areas and protocol. Your practitioner will explain how polynucleotides work at a cellular level and set realistic expectations.
Your Safety, Our Standard
Clinical rigour underpins every appointment at Éclat & Harmonie Studio Clinic.
Qualified Practitioners
All treatments administered by qualified, registered aesthetic practitioners with verified credentials and ongoing professional development.
Prescriber-Led Clinic
Every injectable treatment at Éclat & Harmonie is prescribed by a qualified independent prescriber, ensuring full clinical oversight and patient safety.
Private Studio Setting
Your appointment takes place in a private, single-client studio. No waiting rooms, no overlap. Your treatment time is exclusively yours.
Personalised Consultation
Every new client begins with a thorough face-to-face consultation. We assess your goals, medical history, and suitability before any treatment is agreed.
Aftercare Included
Post-treatment aftercare guidance and follow-up support are included with every procedure. Your practitioner is available if you have any concerns.
Key Benefits
Works at a cellular level, regenerating tissue rather than masking the signs of ageing
Particularly effective for delicate under-eye skin where other treatments can't safely go
Long-lasting results (12+ months) that continue to improve after your final session
A thorough consultation ensures this advanced treatment is correctly matched to your needs
Versatile: treats skin laxity, dullness, fine lines, and hair thinning
Performed with precision in a private studio. The unhurried approach this treatment deserves
Pricing
| Polynucleotides | Price |
|---|---|
| Under-eye Rejuvenation | £250 |
| Full Face Rejuvenation | £300 |
| Neck Bio-Modulation | £300 |
| Décolleté Rejuvenation | £300 |
| Hands Rejuvenation | £250 |
| Hair Growth Stimulation | £300 |
| Face & Neck Combo | £490 |
| 3 Sessions Package (£200+ treatments) | £650 |
| 3 Sessions Package (£300+ treatments) | £750 |
Not sure if this treatment is right for you? Start with our free AI Skin Analysis →
Who Is It For?
- •You've noticed your under-eye area looks darker, more crepey, or more hollow than it used to
- •Your skin has lost its bounce and firmness, and topical products aren't making a difference
- •You're experiencing hair thinning and want a non-surgical approach to stimulate regrowth
- •You'd like a treatment that improves your skin's biology, not just its surface appearance